The Sixers did a great job to restrict the Strikers to 8/119 but were unable to chase that down at Drummoyne Oval on Sunday finishing 9/105.
Batting first, Adelaide was 6/56 in the 13th over and advantage was with the Sixers. Captain Ellyse Perry (3-14) claimed three of those wickets.
South African allrounder Marizanne Kapp (1-24) took the key wicket of allrounder Tahlia McGrath, for a duck in the first over, with a trademark delivery that cut back between bat and pad to hit the top of middle and off stump.
Dubbo pace bowler Emma Hughes (1-12) made her Sixers debut on Sunday and Madeline Penna (16) became her first WBBL wicket.
Wicketkeeper-batter Tegan McPharlin made a crucial 41 not out down the order to lead the recovery for the Strikers.
Strikers’ captain Megan Schutt starred with the ball returning 3-7 from four overs.
Ashleigh Gardner was substituted out of the match during the Sixers’ fielding innings with concussion.