Reigning WBBL champions Brisbane Heat prevailed by 92 runs over the Sydney Sixers on Saturday night at North Sydney Oval.
Brisbane dismissed the Sixers for 73 in the 15th over defending 6/165.
Nineteen-year-old leg-spinning allrounder from New Zealand, Amelia Kerr, ran through the Sixers lower order claiming 3-8 from three overs in her debut WBBL match.
Seeking to turn around the Grand Final result of last season, captain Ellyse Perry gave the Sixers some hope moving to 27 from 30 balls before her Australian teammate, spinner Jess Jonassen (2-12) removed her in the 13th over.
The Sixers lost their last six wickets for one run on a disappointing night.
Australian opening batter Beth Mooney showed her class with a polished 50 from 45 for the Heat, and a rapid fire 36 not out from 17 by allrounder Laura Harris was key for the victors, after the Sixers pegged back the run rate somewhat.
The highlight for the Sixers in the field was the glovework of Alyssa Healy. Two technically perfect stumpings removed Mooney and big hitter Sammy-Jo Johnson.
Sixers teenager Hayley Silver-Holmes claimed best figures with 2-35 from four overs utilising subtle changes of pace.
The Sixers next meet the Melbourne Stars who lost to the Hobart Hurricanes on Saturday afternoon.
Sixers host the Stars at Hurstville Oval next Saturday afternoon.