Having been sent into bat, the Sixers innings started in far from ideal fashion with wicketkeeper Peter Nevill falling for a golden duck after edging to Afghani offspinner Mohammad Nabi in the first over.
Opening partner Jason Roy followed soon after, lofting a Dwayne Bravo delivery to mid-off where Aaron Finch took a brilliant juggling catch.
Nic Maddinson (24) looked to dig in but a mix-up with Sam Billings led to him being run out by a 30-metre direct hit from Bravo.
The Sixers couldn't take a trick, with skipper and top-scorer Johan Botha (32 not out) the only batsman to clear the boundary rope as they posted a total of 8/111 from their 20 overs.
In response, the Renegades made light work of the run chase, passing the total with 27 balls to spare. They were lead by Finch (51 of 38 balls) and White (49 offf 44 balls).